Miami CTSI

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What is Translational Research?

Translation is the process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public — from diagnostics and therapeutics to medical procedures and behavioral changes.

Translational science is the field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process.

  • T1 Translation to Humans: Testing basic science discoveries for clinical effect and/or applicability.
  • T2 Translation to Patients: Testing new interventions in human subjects under controlled environments to form the basis for clinical applications and evidence‐based guidelines.
  • T3 Translation to Practice: Research on the application of new interventions or therapies in general practice; research that yields knowledge on best ways to implement new medical interventions in the clinic.
  • T4 Translation to Population Health: Investigations of factors and/or interventions that influence the health of populations; ultimately results in improved health of the public.

What is Clinical Research?

Clinical research is where a researcher interacts directly with a person or group of people to answer specific health questions. Clinical research helps doctors and researchers find new and better ways to understand, detect, control, and treat illness.

Clinical trials are part of clinical research and are critical to advancing medicine. They are research studies involving volunteer participants that evaluate new medical approaches and increase scientific understanding of a wide variety of diseases.

To learn more about clinical trials and to find out how to participate in a study, visit the UHealth clinical trials page.

Addressing Research Challenges

The approach of the Miami Clinical and Translational Science Institute to address challenges and transform research at the University of Miami is as follows:

  • Reengineer the research environment.
  • Provide institutional support for collaborations in research.
  • Provide support and consultation that is investigator-focused.

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